Summary: For the SNP KCTD10_i5642G/C homozygotes for the major alleles (G) had lower HDL-cholesterol concentrations than did carriers of the minor alleles (P = 0.005). Significant gene-diet interactions for HDL cholesterol were found (P<0.001–0.038), in which GG subjects at SNP KCTD10_i5642G/C.