Circular RNAs (circRNAs) are unique transcript isoforms characterised by back splicing of exon ends to form a covalently closed loop or circular conformation. These transcript isoforms are now known to be expressed in a variety of organisms across the kingdoms of life. Recent studies have shown the role of circRNAs in a number of diseases and increasing evidence points to their potential application as biomarkers in these diseases. We have created a comprehensive manually curated database of circular RNAs associated with diseases.The database is unique in many ways. Firstly it provides standard disease nomenclature as per the ICD codes. It additionally lists the assay and PCR primer details including experimentally validated ones as a ready reference to researchers. To the best of our knowledge, circad is the most comprehensive and updated database of disease associated circular RNAs. |
Statistics |
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Number of disease related circRNA: 1388 |
Number of diseases : 150 |
Number of Genes: 720 |
Number of Primers : 625 |
Number of circRNA |
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Homo sapiens: 1270 |
Mus musculus: 66 |
Rattus rattus: 42 |
Sus scrofa: 6 |
Gallus gallus: 4 |
Download Database |
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The link will be active once the paper is published |
User Manual |
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Example search: | ||
circRNA Name | <circRNA Name> | hsa_circRNA_104983, hsa_circ_0000518 |
Gene | gene:<Gene Name> | gene:AKT3, gene:LIN52 |
Locus | <Chr No.>:<Start>-<End> | chr17:59853761-59861785:-, chr7:55142286-55165437:+ |
Organism | organism:<Organism Name> | organism:Human, organism:Mouse |
Disease | disease:<Disease Name> | disease:cancer, disease:Acne |
ICD-10 | icd:<ICD-10> | icd:C50, icd:A15 |
PMID | pmid:<pmid> | pmid:27465405, pmid:26873924 |
Cite this resource: Mercy Rophina, Disha Sharma, Mukta Poojary and Vinod Scaria.(2020) circad: a manually curated database of circular RNAs associated with diseases. Database Accepted (2020) |
Copyright©2020 CSIR-Institute of Genomics and Integrative Biology | VS Lab |